ABSTRACT Hydrological models (HMs) can be applied for different purposes, and a key step is model calibration using objective functions (OF) to quantify the agreement between observed and calculated discharges.Fully understanding the OF is important to properly take advantage of model calibration and interpret the results.This study evaluates 36 OF

Abstract Background Late-life depression (LLD) is a prevalent neuropsychiatric disorder in the older population.While LLD exhibits high mortality rates, depressive symptoms in older adults are often masked by physical health conditions.In younger adults, depression is associated with deficits in pupil light reflex and eye blink rate, suggesting the

A duplex real-time PCR assay was designed for simultaneous detection and genotyping of Mycoplasma pneumoniae (M.pneumoniae).The detection/typing performance 4 Piece King Bed of this duplex PCR method, targeting specific genes for M.pneumoniae type 1 (mpn 459) and type 2 (mpna 5864), was compared to that of the previously published MpP1 real-time PC

A X-wing flapping-wing mechanism with wings flapping symmetrically is designed.The crank slider mechanism is adopted to convert the circular motion of 4 Piece King Bed the crank into the linear reciprocating motion of the straight shaft, and the straight shaft drives the wings on both sides through the rocker to realize the symmetric flapping of th

BackgroundThe importance of advance care planning (ACP) has been highlighted by the advent of life-threatening COVID-19.Anecdotal evidence suggests changes in implementation of policies and procedures is needed Bracket to support uptake of ACPs.We investigated the barriers and enablers of ACP in the COVID-19 context and identify recommendations to